Feiolix® for
native GLP-1 support

Derived from non-GMO New Zealand Feijoas, Feiolix® is available as a versatile freeze-dried whole fruit powder. It supports healthy metabolic functions and assists in reducing weight gain from high fat diets.

18

Studies (Clinicals, In-Vivo, In-Vitro)

24%

Weight reduction in In-Vivo Study

Feiolix has three different pathways that increase GLP-1 secretion in the body. GLP-1 helps to increase satiety, delay gastric emptying, and regulate blood sugar levels. GLP-1 agonists have been researched thoroughly for their weight management potential.

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Feiolix contains high concentrations of bioactives which impact glucose levels in the bloodstream by increasing insulin secretion, inhibiting glucagon release (prevent blood sugar levels from getting too high), and sensitising receptors to glucose, decreasing insulin resistance.
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NZ Feijoas contain 114% more abscisic acid than any other fruit. Abscisic acid is one of our key bioactives that naturally stimulates GLP-1 production, amongst other things. Our proprietary processing protects the abscisic acid and passes its benefits on to Feiolix consumers.
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Feiolix and it’s bioactives’:

Feiolix contains 3 key bioactives that helps with metabolic regulation

  • Abscisic Acid
    • Increases energy usage by increasing thermogenesis in humans.
    • Binds to the GLUT4 in skeletal and adipose cells. ABA sensitises GLUT4 to glucose in the blood stream and increases the amount of glucose absorbed from blood stream
    • ABA binds to LANCL2 and increases insulin secretion and ultimately absorption of glucose from the blood stream.
    • ABA triggers the secretion of GLP-1
    • Inhibits NFkB which leads to less disruptive hunger signalling and leading to feelings of satiety
  • Polyphenols (Specifically ellagitannins and catechins)
    • Converted to bioavailable urolithins, which promote insulin and GLP-1 secretion
    • Bind to the bitter taste receptors in the intestine promoting GLP-1 secretion
    • Inhibit NFkB to lead to feelings of satiety
  • Dietary Fibre (Xylans and Xyloglucans)
    • Provide food to the microbiome that is converted into SCFA’s
    • Triggers the release of GLP-1 and PYY
    • PYY inhibits ghrelin , a hunger promoting hormone

Read more about the mechanism of actions here:

Feiolix®
is a patented ingredient

A method of lowering serum glucose

A method of lowering blood pressure

Preventing or lower obesity

Ameliorating symptoms of diabetes

Feiolix® and Healthy Ageing

Managing your weight has so many downstream effects. Explore how Feiolix can help mitigate the effects of unhealthy ageing on your body.

Opportunity to Formulate with Feiolix®

Kick-start your NPD process with scientifically researched formulation concepts (backed by health claims). Inside find formulation concepts, complimentary ingredients, and format options!

Webinar

A New Natural Solution for
Boosting GLP-1: Scientific Results (Preview)

Learn how Feiolix is a natural GLP-1 agonist, and what benefits it can offer for weight management

Continuous Blood Glucose Monitor Market Acceptance Testing

We have continuous glucose monitoring (CGM) data demonstrating how Feiolix affects post-meal glucose response. The results provide promising insights into how Feiolix supports healthy glucose levels after eating. Please contact us for more information.

Feiolix and Clinical

Our latest clinical, The Ferdinand Study, has recently been completed in collaboration with the University of Auckland and the High Value Nutrition Unit The study was a randomized, double-blinded, placebo-controlled, parallel-arm clinical trial. There were 97 participants ranging from 18-75 years old with fasting plasma glucose levels in the prediabetic range. Participants  consumed Feiolix (1150mg) or placebo over the 6 month course of the study. In the first two months participants were on a low energy diet (800 calories a day) designed to lower weight and metabolic markers significantly and then for the following 4 months, participants were on a weight manteninace diet. The point of this design was to see if Feiolix could help with the rebound effect. 

Key Takeaways: 

  • Feiolix significantly reduced fasting plasma glucose compared to placebo over 6 months.
  • 185% improvement in FPG in Feiolix group compared to placebo  at 6 months
  • Feiolix led to significant reduction in systolic blood pressure compared to placebo 
  • 9mmHG reduction in 2 months, equivalent to a reduction in risk of major cardiovascular events by 20%
  • No significant safety concerns were reported at the studied dose.
  • This study supports Feiolix’s positioning as a safe, effective ingredient for supporting metabolic health in at-risk populations.
Beyond an ingredient

Why Feiolix® is your best choice?

Clinically proven effectiveness

Market Acceptance Testing Platform

Fantastic taste

Long Shelf-life (36 months)

Noticeable improvement in satiety after one dose!

How does Feiolix® work?

Feiolix® activates GLP-1 secretion and insulin secretion, amongst many other benefits. It has been tested in pre-clinical models of diabetic and leptin deficient mice. Outcomes of Feiolix® consumption were:

  • Feiolix® significantly (P <00.5) reduced the amount of weight gain (24% less than non-Feiolix® extract-fed obese mice) compared to placebo

  • Feiolix® significantly (P < 0.05) decreased the food efficiency ratio (conversion of food to body weight) compared to placebo

  • Feiolix® significantly (P <0.05) cholesterol and triglycerides levels compared to placebo

  • Feiolix® significantly improved insulin resistance compared to placebo

  • Feiolix® significantly (P < 0.01) decreased pro-inflammatory cytokines interleukin-4 (IL-4) and tumour necrosis factors

Read more about our in-vivo work:

Pre-Clinical Dosage Study Summary:

Test your finished products before

COMMERCIALIZING IT!

You can use our exclusive Market Acceptance Testing Platform with your target audience to check for effectiveness and gather feedback/ reviews of your product before it goes ‘live’.

It All Starts With an email!

For any kind of queries, Please contact us

+64 9 520 0831

Level 1, 272 Parnell Road, Parnell, Auckland 1052, New Zealand

info@anagenix.com